Euro-BioImaging is expanding its imaging technology offer!
Euro-BioImaging has launched a Proof-of-Concept study - to provide users access to a number of new imaging technologies. We are currently accepting applications to use these technologies as part of the Proof-of-Concept study at different Euro-BioImaging Nodes. We strongly encourage you to apply, and benefit from the help of the experts at our Nodes. Your participation allows us to validate new technologies and allows you to take advantage of the latest breakthroughs in imaging research.
About Euro-BioImaging’s Proof-of-Concept study
Available technologies
Who should apply?
How to apply?
Funding opportunities
Available technologies
CARS
Are you working on living cells and tissues? Would you like to try a faster technology than confocal Raman mapping? You should try Coherent Anti-Strokes Raman Scattering (CARS) microscopy at our Nodes in Prague and Helsinki!

Dalibor Pánek, Ph.D., from Imaging Methods Core facility at BIOCEV, Faculty of Science, Charles University, explains some of the advantages of this label-free technique for studying sub-cellular structures, and explores potential applications. Dalibor Pánek, Ph.D., from Imaging Methods Core facility at BIOCEV, Faculty of Science, Charles University, explains some of the advantages of this label-free technique for studying sub-cellular structures, and explores potential applications.Dalibor Pánek, Ph.D., from Imaging Methods Core facility at BIOCEV, Faculty of Science, Charles University, explains some of the advantages of this label-free technique for studying sub-cellular structures, and explores potential applications. Learn more here

Antti Isomäki, of the Biomedicum Imaging Unit of Helsinki BioImaging, part of Euro-BioImaging’s Finish Advanced Light Microscopy Node, explains that CARS is an extremely powerful technique in imaging pharmaceutical materials - to analyze drug crystallization and its influence in dissolution of tablets. Learn more here
QPI
Are you working on drug testing, cell interactions or cancer cell biology? Try out Quantitative Phase Imaging in Prague!
Helena Chmelová, Ph.D., from Light Microscopy Core facility at Institute of Molecular Genetics, Prague, Czech Republic, part of Euro-BioImaging’s Advanced Light And Electron Microscopy Node Prague, explains how Quantitative Phase Imaging (QPI) is very useful for studying cell shape, viability, motility, polarity, growth or differentiation under various conditions. Learn more here
SIM
Would you like to study intracellular structures in super resolution? Try out Structured Illumination Microscopy (SIM) in Prague!
Ivan Novotný, Ph.D., from Light Microscopy Core facility at Institute of Molecular Genetics, in Prague, introduces us to Structured illumination microscopy (SIM) imaging technology to visualize intracellular structures. Learn more about how it compares to other super-resolution techniques, and what applications it can be used for: https://www.eurobioimaging.eu/news/sim-fast-and-rather-easy-super-resolution-microscopy/
MSI
Want to analyze metabolite or lipid distribution across tissue sections? Why not try out Mass-Spectrometry-based Imaging (MSI) at our Italian Node in Naples?
The power of MSI is that it enables us to perform studies of metabolomics, proteomics and lipidomics without needing to tag the molecules of interest. Our expert, Seetharaman Parashuraman, Head of the Bioimaging facility of the Institute of Biochemistry and Cell Biology, Naples, an institute belonging to the National Research Council, part of our Advanced Light Microscopy Italian Node, gives some hints on sample preparation and explains the advantages of this technology. Read more here
PAI
Are you studying tissues or organs? Do you want to try a technology capable of penetration like ultrasound with the high contrast of optical imaging? Why not try Photoacoustic Imaging (PAI) in our Multi-Modal Molecular Imaging Italian Node?

Photoacoustic imaging (PAI) is an emerging and powerful technology with a wide spectrum of applications in the field of in-vivo imaging. Enzo Terreno, Coordinator of the Multi-Modal Molecular Imaging (MMMI) Italian Node explains the advantages of this important in vivo imaging technology for applications like oncology, cardiovascular biology, development biology, skin analysis, and abdomen analysis. He invites users to try this technology in Pisa, Torino or Napoli. Read more here
AFM
Working with membranes? Need a technology with vertical and lateral resolution in the nanometer range and requiring only a small number of acquisitions? Try Atomic Force Microscopy in France or Finland!

Atomic Force Microscopy (AFM) is a technique allowing the characterization of sample morphology at nanoscale. Images are acquired by raster scanning a nanometric tip in gentle contact or intermittent contact with the sample. By measuring the tip-sample interaction force as a function of the tip-sample distance, AFMs can evaluate sample elastic and viscous properties. This technology is available via Euro-BioImaging in France and in Finland. Learn more here
Camilo Guzmán, manager of the
Finnish Advanced Light Microscopy Node explains that AFM is one of the most suitable instruments for experiments where molecular binding forces need to be measured or where the mechanical properties of a material need to be characterised at a micrometric scale and under very low forces (pN to nN). AFM not only is very precise, but it is highly versatile to different materials and samples and furthermore it can be combined with fluorescence microscopy to give a full description of the sample that is being tested.
Magnetoencelography (MEG)
Magnetoencephalography (MEG) measures noninvasively minute magnetic fields produced by neuronal activity of the brain. Source modelling is used in MEG to model, quantify, and localize sources contributing to the measured magnetic fields at ms temporal resolution and a few mm spatial resolution. The potential clinical and research uses include for example studies of the functions of neural oscillations, the nature of event-related brain activation, mechanisms of functional connectivity between regions and the emergence of modes of network communication in brain systems.
Case study from our Node: Key imaging technology for understanding neuronal processing directly in a non-invasive fashion
Who should apply?
All scientists, regardless of their affiliation, area of expertise or field of activity can benefit from Euro-BioImaging’s pan-European open access services.
How to apply?
Potential users of these new technologies are encouraged to submit project proposals via our website. To do so, you can login to access our application platform, choose the technology you want to use and the facility you wish to visit, then submit your proposal. All applications will be processed by the Euro-BioImaging Hub. As usual, users will benefit from advice and guidance by technical experts working at the Nodes, training opportunities, and data management services.
How to fund your visit to one of Euro-BioImaging’s Nodes?
Euro-BioImaging is pleased to offer dedicated funding for Euro-BioImaging user projects which can include travel costs and access costs:
• Italian fund for Euro-BioImaging user access grants
In addition, a number of relevant short-term travel are available from Euro-BioImaging Nodes and the imaging community. Please visit the Funding User Access page of our website for a complete overview.