Correlated Imaging Series: Multimodal imaging of human retina pathology

October 24, 2022
Multimodal Imaging Virtual Pub

On Friday, October 28th at 13:00 CEST, Kevin L. Schey, PhD, Department of Biochemistry, Vanderbilt University, delivers a lecture on “Multimodal imaging of human retina pathology,”as part of the Correlated Imaging Series, brought to you by COMULIS and Euro-BioImaging.


Retina deposits form with age and their presence is the highest known risk factor for the development of age-related macular degeneration (AMD); the leading cause of blindness in older adults. Deposits, such as drusen and basal laminar deposits, form below the retinal pigmented epithelium (RPE) whereas deposits, such as subretinal drusenoid deposits (SDD), form above the RPE. The molecular composition of such deposits, which are only partly known, varies depending on their regional and laminar locations. Thus, accurate localization is essential for interpreting imaging mass spectrometry (IMS) results. Furthermore, given the exquisite architecture of the retina, a multimodal imaging approach is required to establish the localization of IMS signals. The general goal of this study is to use multimodal imaging methods including ex vivo OCT, autofluorescence, optical microscopy, and state-of-the-art IMS methods to elucidate the molecular composition of different retinal deposits in aged human tissue. Such information can molecularly inform clinical imaging modalities.

Friday, October 28th, at 13:00 CEST

Join via internet: or via phone:

Meeting ID: 760 003 029 Find your local number:

About Kevin Schey: 

Kevin L. Schey, Ph.D, is Professor of Biochemistry, Chemistry, and Ophthalmology & Visual Sciences at Vanderbilt University. He earned his Ph.D. from Purdue University in 1989 and has 30+ years of professional experience in mass spectrometry and analytical chemistry, including all aspects of proteomics analysis and mass spectrometry imaging. His application area of interest is the eye, particularly lens and retina biochemistry. He directs the Core Facility operations of the MSRC.

More news from Euro-BioImaging

Euro-BioImaging's Head of Image Data Services, Aastha Mathur, with the team at the Hospital La Fe, part of our Population Imaging Node Valencia.

July 23, 2024

Visiting the Euro-BioImaging Spanish Nodes

With summer came the season of conferences and workshops, taking the Euro-BioImaging Hub team across Europe. Head of Image Data Services, Aastha Mathur, took…

July 12, 2024

Latest developments in cryo-EM and a goodbye to iNEXT-Discovery

The final consortium meeting of the iNEXT-Discovery project took place in Brno in June 2024, alongside the Symposium on Recent Advances in Cryo-EM. This…

July 10, 2024

Contribute to the "Inner Cosmos" art project

Inner Cosmos is an art project by Euro-BioImaging aimed at reaching the general public. The video has been designed as part of an installation…