WORLD OF IMAGING – Euro-BioImaging visits the Danish BioImaging Node

March 28, 2023
Danish BioImaging Node Multimodal Imaging

Euro-BioImaging is delighted to share some stories from our fantastic Nodes. First on the long list is the Danish BioImaging Node (DBI). Euro-BioImaging visited the Node and got a two-day tour of their fascinating facilities from Clara Prats, Director of the DBI-INFRA and Director of Light Microscopy and Image Analysis at the University of Copenhagen, and Sonia Garcia, Coordinator of the DBI-INFRA. Clara and Sonia were superb hosts. We filmed what we saw while visiting some of their facilities. Don’t miss our video below and read the article to learn what Danish BioImaging has to offer.

Danish BioImaging is a multi-sited, multimodal Euro-BioImaging Node that brings together five state-of-the-art facilities representing the bioimaging infrastructure of Denmark. The Node provides a broad service offer covering a wide range of advanced bioimaging technologies - from pre-clinical imaging of big animals and humans to cryo-electron microscopy for single particle analysis. Its fields of expertise cover plant biology, HCS of yeast libraries, zoology, pathology, neurosciences and metabolism. In addition, data storage, management and image analysis are a high priority at the DBI Node.

One of the more special features in Danish BioImaging Node is the Bioimaging Core Facility at the Aarhus University Hospital, where surgery rooms are located next to scanners, which Euro-BioImaging users can access and image all kind of animal models and also get access to medical and surgery support. The Danish Molecular Biomedical Imaging Center at the University of Southern Denmark offers some state-of-the-art super resolution methods, such as STED, PALM and single-molecular localization, while also being specialized in home-built systems.

The Center for Advanced BioImaging is specialized in plant biology and yeast. They have a fascinating system up and running; a spinning disk with a vertical stage and with a light controlled software, long-term experiments, such as root growth can be done. The Core Facility for Integrated Microscopy at the University of Copenhagen offers a broad range of applications from electron microscopy to light sheet microscopy with a highly established pathology imaging services with slide scanners, a pathology lab and a combination of deep learning and pixel classification.

On top of all this, the Danish BioImaging Node is very focused on image analysis and are planning to open up image analysis services for people in Denmark and around Europe that will be done in collaboration with computer scientists.

In addition to providing access to advanced imaging technologies, the Danish BioImaging Node is committed to fostering collaboration and knowledge exchange within the scientific community. Through Euro-BioImaging, researchers can request access to the Node's instruments, attend workshops and training courses, and engage in joint research projects. This collaborative atmosphere promotes the rapid dissemination of knowledge and the development of new imaging techniques.

View over Copenhagen from the University of Copenhagen
The Core Facility for Integrated Microscopy with a nice Euro-BioImaging sign
Jana Harizanova inserting samples into the LS7 Light Sheet microscope
The CM 100 electron microscope
The facility needed an extra tall room to fit the Titan Krios transmission electron microscope
Clara Prats, Sonia Garcia and Michael Pedersen in the maze of the Aarhus University Hospital
An axolotl waiting the get an ultrasound on its heart
Ongoing patient MRI screening
Another MRI in use for research
Surgeons and their students during their hands-on course

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