Tech Exchange with Cellsense Technologies

On 8th May 2026, we are welcoming Raimund Schlüßler  from Cellsense Technologies for a presentation on "Brillouin Microscopy: A Tool for 3D Imaging in Mechanobiology".

Abstract

In recent years, Brillouin imaging has rapidly advanced, finding new application areas thanks to its capability to measure mechanical parameters in three dimensions and on live samples. We present initial results obtained with our newly developed Brillouin microscope, which integrates this technology with existing optical imaging methods.

3D organoid with sections and fluorescence.

Image credit: CellSense Technologies.

We showcase several examples, including single-cell measurements and tissue sample analyses. Its 3D capability makes this method particularly valuable for 3D cell culture applications, with initial results on complex organoids being presented. Additionally, there is a growing number of applications in plant physiology, and we will share results using the Arabidopsis root model system.
In summary, Brillouin microscopy is a versatile tool that can visualize differences in mechanical properties, quantify them, and observe dynamic events on time scales relevant to developmental biology.