Volume EM Series: Neuropathology on tape – applications of ATUM-based volume EM


Published December 1, 2022
Technology
Scientific application
Category

On Friday, December 16th at 13:00 CET, Martina Schifferer, of SyNergy Nanoscale Hub, Technical University Munich and German Center of Neurodegenerative Diseases, delivers a lecture on “Neuropathology on tape – applications of ATUM-based volume EM” as part of the Volume EM Series, brought to you by the Volume EM community and Euro-BioImaging.

Abstract

Volume Electron Microscopy (vEM) reveals biological structures at nanometer resolution in three dimensions and resolves ambiguities of two-dimensional representations. However, as the structures of interest – like disease hallmarks emerging from neuropathology – are often rare but the field of view is small, this can easily turn a vEM project into a needle in a haystack problem. With array tomography methods like Automated Tape Collecting Ultramicrotomy (ATUM) SEM (ATUM-SEM), serial ultrathin sections are collected onto tape and into a storable tissue library, thereby enabling repetitive imaging at different resolution levels for an SEM-based search strategy. This virtual pub talk will introduce the ATUM-SEM method, its applications in targeted and correlated neuropathology and explore future directions in the examination of nervous system tissue on tape.

Friday, December 17th at 13:00 CET

Register to get the connection information:  https://us02web.zoom.us/meeting/register/tZAucuCspzktEtZyWJ09W6xNGuXVOusLWqcq 


More news from Euro-BioImaging

CanSERV user story

August 27, 2025

Multiplex imaging of lymph nodes: How Euro-BioImaging is advancing cancer research through the canSERV funding

The immune system plays an important role in fighting cancer but can also be a pathway of metastasis – therefore understand the interactions of…

August 26, 2025

Euro-BioImaging at IUIS 2025: Building Bridges with the Immunology Community

Vienna, August 17–22, 2025 – More than 5,000 researchers from over 150 countries gathered in Vienna for the 19th International Congress of Immunology…

Euro-BioImaging booth at Turku PET Symposium 2025

August 11, 2025

Euro-BioImaging at Turku PET Symposium 2025

In June 2025, Euro-BioImaging team members were delighted to attend the Turku PET Symposium, organised by the Turku PET Centre, part of our Finnish…