We are very pleased to announce that the Euro-BioImaging family is growing! In June 2021, we welcome a total of eight new Nodes to the Euro-BioImaging family, including two Mixed, five Biomedical, and one Biological Imaging Node. These new Nodes are located in the Czech Republic, Denmark, Hungary, Israel, Italy, the Netherlands, Poland, and Portugal. In addition, the AMMI Maastricht Node (Netherlands) was granted an upgrade, to bring a new facility on board and expand their technology portfolio. Preparations are now underway to enable users to apply to the new Nodes and upgraded Node technologies as soon as possible.
These imaging facilities became part of Euro-BioImaging after a stringent review process by the Euro-BioImaging Scientific Advisory Board. As part of the Euro-BioImaging ERIC, the services provided by these facilities will be open to all scientists, regardless of their discipline or affiliation. We congratulate the successful new Nodes and upgraded Node and look forward to welcoming users at these excellent facilities.
The Center for Advanced Preclinical Imaging (CAPI) at the Charles University in Prague is a single-sited, multimodal Node covering a wide range of biomedical imaging modalities at the preclinical level. It is equipped with X-ray, CT, MRI, MPI, PET, SPECT, optical imaging, ultrasound and photoacoustic imaging instruments. All the technologies can be combined to image single animals and co-registered images can be obtained.
Danish BioImaging is a multi-sited, multimodal Node bringing together five facilities across the country, representing the joined national imaging infrastructure of Denmark. The Node provides a broad service offer covering a wide range of advanced and state-of-the-art bioimaging technologies - from pre-clinical imaging of big animals and humans to cryo-electron microscopy for single particle analysis. The facilities of this Node bring expertise in many fields, including plant biology, high-content screening of yeast libraries, zoology, pathology, neurosciences and metabolism. In response to the increase in size and complexity of image-based data sets produced by single and multimodal bioimaging technologies, image analysis is a key part of the Danish BioImaging offer.
The Medical and Preclinical Imaging Hungary is a multi-sited, multimodal Node covering a full range of biomedical imaging techniques. The specialty of the Node is functional imaging. Each site specializes in at least one technique in which it has high expertise: quantitative autoradiologic measurements, microCT, PET, clinical SPECT/CT and PET/CT.
The Israel Bioimaging Node is a multi-sited, multimodal Node including seven host sites across Israel. It offers access to a broad range of technologies from biological and molecular to medical imaging. The focus and unique aspect of Israel Bioimaging is to facilitate and enable cross-modality imaging spanning all scales. Israel Bioimaging encompasses seamless correlative imaging from electron microscopy and advanced light microscopy through advanced live and high throughput imaging to in vivo preclinical and clinical imaging. Israel Bioimaging also has a capacity for advanced image analysis and computation.
The Digital Imaging Multimodal Platform Neuromed - DIMP NEUROMED is a single-sited, multimodal Node aiming to provide access to an integrated digital analysis support for preclinical and clinical studies in the field of neuroscience, extending from the study and evaluation of animal models to their translation into clinical practice. The Node provides access to imaging technologies and molecular probes, producing digital images which are analyzed in a dedicated High Performance Computing System. Users can either perform their preclinical and population imaging studies using the measurement and analysis infrastructure, or take advantage of the large database of preclinical and clinical digital images in order to test their hypothesis with artificial intelligence tools developed by Neuromed.
TThe Dutch High Field Imaging Hub is a multi-sited, single modality Node, offering high field MRI infrastructure for human imaging. It is a front-runner in precision MRI focusing on medical and neuroscience using advanced MRI methodologies. The four imaging centers are equipped with ultra-high Field MR instruments that can be used to obtain ultra-high resolution images of the brain, spine, breast, heart, abdomen and extremities, and benefit from increased signal to noise and contrast associated with higher magnetic field strengths. These centers work together to exchange imaging protocols, data processing technology and RF coil technology to expedite the further development of high precision imaging.
The Brain Imaging network (BIN) – Portugal is a single modality Node, offering open access to PET and MR technologies for human imaging, with particular focus on neuroimaging. The Node provides expertise in the development of new radiolabeled molecules that can be used as tracers for processes that cannot currently be studied with PET. Work is complemented by studies on developing new nuclides on the cyclotron to respond to new clinical and research needs and also services to the local pharmaceutical companies regarding pre-clinical testing of new, candidate drugs currently under development.
The Advanced Light Microscopy Polish Node is a multi-sited, multimodal biological imaging Node hosted at 3 institutions in Warsaw and Krakow. The Node has broad expertise in leading light and electron microscopy techniques, including functional imaging, correlative light and electron microscopy, high-throughput microscopy and super-resolution. The particular scientific focus of the Node lies in the study of subcellular and cellular dynamic processes and cell and tissue physiology.
The AMMI Maastricht Node has been upgraded with inclusion of the Imaging Mass Spectrometry division at M4I. This facility offers a unique infrastructure for state-of- the-art mass spectrometry based molecular imaging. Complementary imaging modalities allow determination of the spatial distribution of biomolecules from cellular and tissue surfaces with spatial resolutions ranging from 50 nm to 200 μm. The range of desorption and ionization methods available allow analysis of a variety of complex surfaces ranging from single cells to larger histological tissue sections. Investigations of the structure-function relation of biomolecules in their tissue environment using MS image guided laser capture microdissection are also possible.
At regular intervals, Euro-BioImaging invites applications from imaging facilities located in Euro-BioImaging ERIC member countries via its Call for Nodes. In addition, existing Euro-BioImaging Nodes can apply for an upgrade to include new facilities within their Node structure.
In the Call for Nodes, applicants are evaluated by the leading international experts on our Scientific Advisory Board on a wide variety of factors, including:
Following successful evaluation and approval by the Board, the Nodes join the Euro-BioImaging family by signing service level agreements that outline the services to Euro-BioImaging users. This multi-step process guarantees a top-notch research infrastructure and a high-level of service for users.